Don Sin


Dr. Sin is a chest physician and a clinical epidemiologist, who works primarily with large databases. In close collaboration with Dr. Paul Man, he also conducts research using a "wet" laboratory to analyze serum samples from chronic obstructive pulmonary disease (COPD) patients for various markers/mediators of systemic inflammation to better understand the link between COPD and cardiovascular diseases.

Dr. Sin graduated from the University of Alberta in 1991 (MD), and specialized in Internal Medicine and became certified in Respirology in 1997. He obtained an MPH degree at Harvard University and did his post-clinical training at University of Toronto.

His major areas of research interest include:

  • evaluating novel therapies for management of patients with COPD, with an emphasis on anti-inflammatory agents.
  • evaluating novel biomarkers of systemic inflammation in COPD patients
  • evaluating the potential role of systemic inflammation in the pathogenesis of cardiovascular complications among COPD patients